Synthelabo to Sanofi-Aventis *****
Head of the Neurochemistry group and then head of the Neuroscience Genomics group

B.Sc Zoology Leeds University 1974
M.Sc Pharmacology and Toxicology Bradford University 1976
PhD Pharmacology University of Bristol 1979

Postdoctoral studies:
Department of Neurology: Institute of Psychiatry, London *****
Fellowships awarded:
Parkinson's disease Society
Association to COMBAT Huntigton's chorea (UK)
National Huntington's disease association (USA)

A selection of published articles:-
***** C.J. (2006) Schizophrenia susceptibility genes converge on interlinked pathways related to glutamatergic transmission and long-term potentiation, oxidative stress and oligodendrocyte viability. Schizophr. Res. 86, 1-14.

***** C.J. (2007) Multiple genes and factors associated with bipolar disorder converge on growth factor and stress activated kinase pathways controlling translation initiation: implications for oligodendrocyte viability. Neurochem. Int. 50, *****.

***** C.J. (2007) eIF2B and oligodendrocyte survival: where nature and nurture meet in bipolar disorder and schizophrenia? Schizophr. Bull. 33, *****.

***** C.J. (2007) Convergence of genes implicated in Alzheimer's disease on the cerebral cholesterol shuttle: APP, cholesterol, lipoproteins, and atherosclerosis. Neurochem. Int. 50, *****.

***** C.J. (2008) Interactions between the products of the Herpes simplex genome and Alzheimer's disease susceptibility genes: relevance to pathological-signalling cascades. Neurochem. Int. 52, *****.

***** C.J. (2009) Schizophrenia susceptibility genes directly implicated in the life cycles of pathogens: cytomegalovirus, influenza, herpes simplex, rubella, and Toxoplasma gondii. Schizophr. Bull. 35, *****.

***** C.J. (2010) APP, APOE, complement receptor 1, clusterin and PICALM and their involvement in the herpes simplex life cycle. Neurosci. Lett. 483, *****.

***** C.J. (2010) Alzheimer's disease plaques and tangles: Cemeteries of a Pyrrhic victory of the immune defence network against herpes simplex infection at the expense of complement and inflammation-mediated neuronal destruction. Neurochem. Int.58,*****

***** C.J. (2010) Alzheimer's disease: a pathogenetic autoimmune disorder caused by herpes simplex in a gene-dependent manner. Int. J. Alzheimers. Dis. 2010, http://www.ncbi.nlm.nih.gov/pubmed/*****

***** C.J. Epstein-Barr and other viral mimicry of autoantigens, myelin and vitamin D related proteins, and of EIF2B, the cause of vanishing white matter disease: Massive mimicry of multiple sclerosis relevant proteins by the Synechococcus phage. Immunopharmacol.Immunotoxicol. Pubmed in progress
. 2011. http://www.ncbi.nlm.nih.gov/pubmed/*****

***** C.J. Pathogen and autoantigen homologous regions within the cystic fibrosis CFTR protein suggest an autoimmune treatable component of cystic fibrosis. FEMS Immunol.Med.Microbiol. in press. 2011. http://www.ncbi.nlm.nih.gov/pubmed/*****

***** C.J. The fox and the rabbits, environmental variables and population genetics.1: Replication problems in association studies and the untapped power of GWAS. 2: Vitamin A deficiency, herpes simplex reactivation and other causes of Alzheimer's disease. ISRN Neurology . 2011. http://*****/isrn/neurology/aip/*****/

***** C.J. Schizophrenia: A pathogenetic autoimmune disease caused by viruses and pathogens and dependent on genes. J.Pathogens , in press. 2011.

Dexter D.T., ***** C.J., Wells F.R., Javoy-Agid F., Agid Y., Lees A. et al. (1989) Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J. Neurochem. 52, *****.