Ian ***** has considerable experience in drug discovery, development and diagnostics gained over 29 years within the biotechnology, diagnostic and pharmaceutical industries in the UK. His experience spans many therapeutic areas including cancer, inflammation, anti-virals, respiratory and thrombosis.

Ian set up ***** , a chemistry service provider, in 1999, and has worked with clients in the pharmaceutical and biotiech industries in Europe, United States and Japan. Work at ***** has contributed to numerous patents, clinical candidates and pre-clinical leads across various indications.

Main areas of expertise:

• Medicinal chemistry and process R & D
• Solid and solution phase (natural and non-natural) peptide synthesis
• Biochemical and biophysical screening
• Peptide, protein and antibody labelling
• Material sourcing including active drugs, fine chemicals and rare compounds

Education

Dr Ian ***** received his PhD from Bath University in 1978 after researching into the synthesis of anti-cancer drugs. His thesis was entitled ‘The Synthesis of Benzoellipticine’. He then undertook Post Doctoral research at The Strangeways Research Laboratory, Cambridge between 1978 and 1982.

Brief career overview

***** . Research Scientist, Amersham International plc.
***** . Section Leader, Advanced Drug Delivery Research Unit, Ciba-Geigy plc.
***** . Senior Scientist, Department of Peptide Preformulation and Delivery, Ciba-Geigy plc.
1991-July 1997. Senior scientist, Department of Thrombosis, Drug Discovery, Ciba plc. and Laboratory Head, Drug Discovery, Novartis, Horsham.
July 1997- August 1998. Head of Chemistry, Antisoma plc.
August 1998 - April 1999. Head of Research and Development, Antisoma plc.
April 1999-September 2001. Science Director ***** Ltd.
October 2001 - November 2004. Chief Scientific Officer, ***** Ltd and Director of Chemistry, KuDOS Pharmaceuticals Ltd.
December 2004 to date, CEO ***** Limited
June 2009 to date, CEO RioTech Pharmaceutical Limited

Dr Ian ***** is the main author on a number of scientific papers and book chapters.

Patents:
1) K. A. Menear, P. W. Taylor, I. T. W. ***** and J. Lowrie. Novel rifamycin as lipid lowering agents. European Patent ER- ***** -A (1987).
2) Lowther, N; Hassan, I; ***** , ITW. Desferrioxamine-B salts and their use as orally effective iron chelators. Patent publication number wo ***** (1995).
3) Felder, E; Rink, H and ***** , I. T. W. Process for the production of combinatorial libraries. wo ***** (1995)
4) ***** , I. T. W. Patent pending, solution phase organic library synthesis and screening.
5) Thrombin inhibitor patent. Filing, May 1997.
6) Adaptation of a PCR cycler for heating and cooling on Chiron Mimitope synthetic PINS. Patent Pending.
7) Various patents filed as a result of work carried out between ***** and KuDOS identifying inhibitors of a number of DNA repair Kinase enzymes.