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Recent Protein Asays Inquiries

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Analytical Assay

We are looking for an analytical assay qualification expert in the development of pharmaceutical and biotechnology processes to meet we acquire, assess, or rapidly and economically develop process technology or production capabilities needed. The expert would able to guide work for analytic assay qualification used for the clinical and commercial manufacture of therapeutic proteins. This expert will plan, provide protocols and advices in support of analytical assays qualification, include development of mass spectrometric techniques, chromatographic and electrophoretic methods, in vitro potency assays to support process development, quality control and physicochemical characterization of therapeutic antibodies and antibody drug conjugates. In addition, the expert knowledge in interim reference standard, glp toxicology (in vivo portion), lot release (qa & qc) and various regulatory submissions including ind, bla, impd, etc. This expert will also be expected to direct the technical activities of junior scientists. A hands-on, laboratory-based effort will be desirable. Areas of expertise: seeking experts with knowledge of analytical assay qualification; analytical assay; biotechnology process; therapeutic proteins; protein synthesis; antibodies; therapeutic antibodies; antibody; biochemist; biochemistry

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    Mohammed |Director

    I have an extensive background in ADC and analytical assay development including biochemical assays....

    5.5 Hours Later
  2. Profile Picture

    Ali |Senior Scientist

    This is my field, both assay develpoment and toxicologocal levels. What are your questions? What are...

    8.9 Hours Later
  3. Profile Picture

    vetury |Professor (retired) and Chief Scientifi

    What you have asked for requires a fulltime job which I no longer do. However, people usually come t...

    16.7 Hours Later
+12 Other Responses
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Protein-ligand Docking

Hello, i am looking for an expert in protein-ligand docking to assist me with a project. I wish to dock two ligands to the delta, mu and kappa opioid receptors (the crystal structures of these receptors are known and are available on rcsb pdb). I have experimental ic50 values for each of the 2 well-known ligands (structural analogues) interacting with with each of the 3 opioid receptors. I would like an expert to help to help explain why these 2 structural analogues behave quite differently when docked to the opioid receptors (greater than 10-fold differences in ic50 values). I can provide the experimental ic50 data. High quality color figures (such as in crystal structure of the âµ-opioid receptor bound to a morphinan antagonist nature. 2012 mar 21;485(7398):321-6) are needed, along with a figure which clearly identifies the key amino acid (or water) interactions. Any additional information to help explain the differences in potency (e.G. Energetics, electrostatics etc..) would also be great. An overall showing how the 2 ligands interact when docked to the 3 proteins would be good too. A time and price estimate would be appreciated. Thank you.

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    Antonio |Staff Scientist

    I have a great deal of expertise in this area. Please contact me here if you are interested in talk...

    1.2 Hours Later
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    Nilesh |Senior Scientist

    Hi I can do this job to your ***** total cost of job will be around five hundred us dolla...

    4 Hours Later
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    Esben |Consultant

    Hi, I want to ask from where you have the IC50 values, and how they were determined? Is it cor...

    5.1 Hours Later
+13 Other Responses
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High Throughput Docking

I am interested in having high-throughput protein docking screening performed on a crystal structure of interest (from the pdb website). I am seeking someone with the expertise and computational tools to allow for screening of very large data-sets (millions of compounds) through the crystal structure. Analysis would include identification of key molecular scaffolds/functional groups that are involved (or not involved) in docking. A method, docking score, statistics, graphs and illustration of structures will need to be provided as well as overall conclusions about the physicochemical properties of molecules/scaffolds that dock with the protein. A time and cost estimate would be helpful. Thank you.

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    Richard |Director of Computational Chemistry

    Hi Paleo, Evotec's *****istry team would be happy to build the baysian model and perfo...

    31 Minutes Later
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    Gerald |Principal Consultant

    I am interested in your request, but before submitting a formal proposal, I would want to know the s...

    48 Minutes Later
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    Anton |CSO

    I can run docking screening on your crystal structure. I will be using ICM – the docking software th...

    2.6 Hours Later
+26 Other Responses
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Collagen Sales

Dear sir/mam, my name is santhosh and i am working as an independent medical device consultant. One of my clients is a manufacturer of collagen and is interested in expanding the collagen sales in different parts of the world, could you please guide me on this issue. Service charges can be discussed. Thanks, kr., santhosh.

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    Akin |PhD, MSc, MBA

    Hi Santhosh, Thanks for your message. I am interested in learning more about your product/informatio...

    8 Minutes Later
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    Harminder |Associate Director

    Hi Santhosh, Thank you for contacting me. I would like to work with you on this project. Please let ...

    9 Minutes Later
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    Carl |Managing Director

    Can you be more specific in understanding the type of collagen market you are interested in? For ex...

    33 Minutes Later
+9 Other Responses
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Protein Analytics And Characterization

This is a 12 month contract opportunity in california: post-doctoral fellow/scientist ii analytical development - protein analytics and characterization overview: as a member of the analytical development team, this position will support early to late stage development focused on protein analytics and characterization. The successful candidate may develop, transfer, and validate protein analytical methods for drug substance and drug product release, stability and characterization. Responsibilities: conduct bench activities for protein analytical characterization of new drug candidates. Optimize, and qualify test methods for assigned projects. May assist with review technical documents including analytical method development reports, method validation protocols and reports, standard operating procedures in compliance with regulatory requirements. Actively support testing of new drug candidates at various stages of development. Participate in technical transfer of assays to qc and process development and contract laboratories in a cgmp or glp environment, if appropriate. Qualifications: phd in relevant field with minimum of 0 to 2 years’ related academic experience in analytical development for the post doc i; the sr post doc will have 2 to 4 years’ of post-doctoral experience. Experience with analytical techniques including but not limited to hplc, ce, spectrophotometric assays, sds-page, elisa and light scattering is desirable. Knowledge of statistical data analysis preferred. Some experience with analytical, technical writing, communication and data management skills are required. Knowledge and/or understanding of working in a glp/gmp highly desirable. Contact us here on zintro for further details.

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    Amy |Zintro Expert

    I was the Director of Protein Services at GlycoSolutions, a cGMP analytical testing lab, where I cre...

    1.6 Hours Later
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    R. |Biotech Research Analyst/Scientist

    What type of proteins do you require some analyses with? Are they overexpressed, ***** syntheti...

    1.8 Hours Later
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    Gerald |Senior Research Chemist

    I have a PhD in organic chemistry and have experience in these type of *****. ...

    8.1 Hours Later
+9 Other Responses
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Protein Purifcation

Want to know about different techniques and about the sequencing.

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    Das |Chief Scientific Officer

    Hi, We offer custom gene synthesis, cloning, sequencing, protein production, ***** relate...

    56 Minutes Later
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    Todd |President, BioAdept

    I am the CEO of a Biotech consulting firm and I believe one of our team consultants can be of assist...

    59 Minutes Later
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    Michael |Biotechnology Consultant

    I have extensive epxerience in protein ***** characterization. Knowledgeable in precipit...

    2.1 Hours Later
+9 Other Responses
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E.coli Expression System

Experience in e.Coli expressed protein purification from inclusion bodies is essential. Experience in cytokines specially interferon beta 1-b purification and formulation process development is desired.

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    Sam |Director of Molecular Biology

    Sir/Madam, I have cloned, expressed, and purified approximately 75 proteins. Inclusion bodies & the...

    1.8 Hours Later
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    ALOKESH |SCIENTIST

    i cannot see your phone number maybe you need to get the premium access...

    18.6 Hours Later
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    Debasish |Associate Professor

    I am an expert on protein expression, purification, I am available for phone consultation....

    1.1 Days Later
+5 Other Responses
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Phage Display

Phage display library construction, selection for scfv binding to small antigens

  1. Profile Picture

    Paul |Principal Scientist and Director, Pharma

    I have not worked directly with either scFv or phage display, but I think I could assist you (depend...

    20.4 Hours Later
+1 Other Responses
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Protein Crosslinking

Hi protein experts out there, i am trying to cross link a small peptide to collagen i (repeat of gly-pro-hydroxypro). How do i do this? Are there other functions than the carboxy terminal that can be used? Thanks. R

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    Harold |Dr.

    oxirane beads or TiO2 can be used for crosslink...

    11.9 Hours Later
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    Bob |Director

    I don't know how I got onto your list of experts but this is WAY outside my area of expertise. I do ...

    1 Day Later
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    Chad |Senior Scientist, Scientific Advisor, Pr

    It somewhat depends on the small peptide you want to crosslink....

    1.8 Days Later
+4 Other Responses
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Protein Purification

Seeking expert with knowledge in recombinant trypsin purification

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    Dr Sumant |Biopharma Biologics Process and Manufact

    i am very much experienced in ***** have more than 15 years experience in protein purific...

    4 Hours Later
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    Mridula |Scientist

    I have years of expertise in recombinant protein *****nitely can help you....

    4.1 Hours Later
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    swamy |medical Writer

    I have an extensive record of purifying recombinant proteins such as Ras, Mek, FT, IDO etc.,...

    4.2 Hours Later
+34 Other Responses
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Analytical Assay Qualification

We are looking for an analytical assay qualification expert in the development of pharmaceutical and biotechnology processes to meet we acquire, assess, or rapidly and economically develop process technology or production capabilities needed. The expert would able to guide work for analytic assay qualification used for the clinical and commercial manufacture of therapeutic proteins. This expert will plan, provide protocols and advices in support of analytical assays qualification, include development of mass spectrometric techniques, chromatographic and electrophoretic methods, in vitro potency assays to support process development, quality control and physicochemical characterization of therapeutic antibodies and antibody drug conjugates. In addition, the expert knowledge in interim reference standard, glp toxicology (in vivo portion), lot release (qa & qc) and various regulatory submissions including ind, bla, impd, etc. This expert will also be expected to direct the technical activities of junior scientists. A hands-on, laboratory-based effort will be desirable.

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    Ali |Senior Scientist

    Good morning, I have PhD in molecular toxciology and work experince in both academic and industrial ...

    11 Minutes Later
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    Vijay Nag |Research Scientist and Quality Manager

    Dear Biotech CEO, i have the experience and capability accomplish the above tasks, plz furnish detai...

    10.2 Hours Later
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    Anthony |Independent Consultant

    Hello, Thank you for contacting me. I am quite interested in learning more about your company and...

    12.4 Hours Later
+19 Other Responses
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Protein Powder Formulation

I am putting together a formulation for a natural superfood protein powder and would like to get some expert advice on the formulation i have come up with, with the aim to answer questions like - would this formulation provide a range of proven health benefits - would the ingredients react with each other okay - is there anything that could be added/removed to make it better - are there any ingredients that are a bit pointless - overall opinion as a high protein, health and wellbeing shake - any other comments

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    Judy Seybold |Zintro Expert

    As a dietitian and food scientist that has guided key consumer goods and pharma companies the past 3...

    41 Minutes Later
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    Jeff |Product Innovation & Development

    Hello, I have years of experience ***** developing products in a number of different cate...

    41 Minutes Later
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    Peter |CEO

    Having run product development for major nutrition companies, I am happy to help. Feel free to check...

    44 Minutes Later
+12 Other Responses
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