Source Protein Ligand Experts for your Project, Phone Consult or Job

Submit an anonymous Inquiry -- Start receiving responses within a few hours

Have a need? Explain it here

Zintro does not display, sell or trade e-mail addresses

An eye iconForgot password?
Submit Inquiry

By clicking Submit Inquiry you agree to our TermsVIEW

or Request Pricing Information

How Zintro Works

  1. 1. Provide a clear description of your needs and your expectations of an expert, consultant or job candidate and Zintro will match it with the most relevant professionals in our platform.
  2. 2. Within a day or two typically 6 - 12 Experts, who have opted-in, will contact you with a brief explanation of their qualifications and how they can help.
  3. 3. You can communicate back and forth, qualify each other, connect and pay fees to Experts through Zintro.
  4. Zintro is free, anonymous and without obligation.

Loved by Thousands

Loved by thousands logos

Need Help?A phone icon1-877-236-7016

Recent Protein Ligand Inquiries

Area Icon

Protein-ligand Docking

Hello, i am looking for an expert in protein-ligand docking to assist me with a project. I wish to dock two ligands to the delta, mu and kappa opioid receptors (the crystal structures of these receptors are known and are available on rcsb pdb). I have experimental ic50 values for each of the 2 well-known ligands (structural analogues) interacting with with each of the 3 opioid receptors. I would like an expert to help to help explain why these 2 structural analogues behave quite differently when docked to the opioid receptors (greater than 10-fold differences in ic50 values). I can provide the experimental ic50 data. High quality color figures (such as in crystal structure of the âµ-opioid receptor bound to a morphinan antagonist nature. 2012 mar 21;485(7398):321-6) are needed, along with a figure which clearly identifies the key amino acid (or water) interactions. Any additional information to help explain the differences in potency (e.G. Energetics, electrostatics etc..) would also be great. An overall showing how the 2 ligands interact when docked to the 3 proteins would be good too. A time and price estimate would be appreciated. Thank you.

  1. Profile Picture

    Antonio |Staff Scientist

    I have a great deal of expertise in this area. Please contact me here if you are interested in talk...

    1.2 Hours Later
  2. Profile Picture

    Nilesh |Senior Scientist

    Hi I can do this job to your ***** total cost of job will be around five hundred us dolla...

    4 Hours Later
  3. Profile Picture

    Esben |Consultant

    Hi, I want to ask from where you have the IC50 values, and how they were determined? Is it cor...

    5.1 Hours Later
+13 Other Responses
Area Icon

Global Catalyst And Ligand Market

We're currently conducting a study on the global catalyst and ligand market, with an emphasis on the european region. In line with this, we look to connect with relevant industrial experts over a paid call on the following parameters: • industry value chain for the catalyst as well as the ligand market. We would be keen to learn the role of contract manufacturers herein. • market landscape in terms of leading producers of catalysts and ligands, including their capabilities. • key success factors for a supplier/ contract manufacturer of ligands and catalysts? • market outlook in terms of challenges faced by existing market players as well as growth drivers, including promising application areas/ reactions. Experts with experience working for johnson matthey, basf se, evonik industries ag, solvias ag, albemarle, süd-chemie and w. R. Grace in europe are highly preferred. We would appreciate a prompt response with the contact information, so that we can share more details on the project. This is on an urgent basis. Thanks.

    +undefined Other Responses
    Area Icon

    Nanoelectromechanical System

    I am looking for a technical review of patents that are focused on nano-electromechanical systems (nems), ligand detection, electrostatic/piezoelectric resonators, and bio sensors. Would like a written opinion of the patent(s) and the technical feasibility of those patents. Each patent consists of approximately 10 pages of written description and 12-16 pages of diagrams.

    1. Profile Picture

      Sean |President

      Chris: The abstract makes sense to me. I have had experience with nanotech for a while as well as se...

      2.2 Hours Later
    2. Profile Picture

      Gareth |President

      My technical background is in MEMS/NEMS for medical *****, including biosensors. My PhD thesi...

      2.4 Hours Later
    3. Profile Picture

      Glenn |Partner

      I have a dozen issued *****, half a dozen pending and have been through two ********** ...

      2.6 Hours Later
    +22 Other Responses
    Area Icon

    Computational Chemistry

    Evaluation of different approaches for ligand-based screening focused on drug reprofiling

    1. Profile Picture

      Melissa |Associate Professor

      Hi reig, I'm interested in discussing with you further about your needs....

      13 Minutes Later
    2. Profile Picture

      Rodney |Biochemist

      Dear reig, I would like more ***** your project, Thank you, Rodney...

      30 Minutes Later
    3. Profile Picture

      Ryan |Principal Scientist

      Hi I have a background in *****istry, have worked as a *****istry support...

      1.8 Hours Later
    +22 Other Responses
    Area Icon

    Protein-ligand Docking

    I need an expert who can perform computational protein-ligand docking for me. I will provide drug candidate structures, and i need the expert to perform docking and provide me the results. (the methods must be clearly documented for use in scientific publications.)

    1. Profile Picture

      Natalya |CEO

      SCHTM has extensive experience combined with modern methods and will be glad to contribute expertise...

      17 Minutes Later
    2. Profile Picture

      Gerard |Head of Cheminformatics unit at CTNS

      We are experts in protein-ligand docking. In fact, we have applied this screening technology as part...

      1.2 Days Later
    3. Profile Picture

      Juzer |Scientist

      Hi, I can work for this project, but then there are many things which are involved here. We need to ...

      1.7 Days Later
    +6 Other Responses
    Area Icon

    Chromatography

    Looking for manufacturing process of protein a chromatography media and protein a ligand

    1. Profile Picture

      Michalis |Head of proteomics facilities

      Please provide me more *****t this inquiry. I might be able to help you....

      18 Minutes Later
    2. Profile Picture

      Natalya |CEO

      Conduct extensive research in this field and will be glad to contribute expertise...

      35 Minutes Later
    3. Profile Picture

      Jay |Applications Scientist

      Why? There are already Asian sources that make Protein A, G, with C terminal Cys for covalent linki...

      4.1 Hours Later
    +7 Other Responses
    Area Icon

    Computational Chemistry And Biology

    Hello, i have a relatively straight forward project that i am hoping to get some help with. I am interested in docking a protein which has a pdb-available crystal structure with 6 known drugs. What i would like for each of the 6 dockings are: (1) a schematic plot/figure showing the docking for each ligand to the active site (2) a predicted ki (3) identification of the amino acids involved in binding and a figure showing this (4) a figure showing the superimposition of the identified ligands (in the absence of the protein) (5) electrostatic potential surfaces of the inhibitors and their binding energies (6) orbital energies/quantum mechanics-related areas. Please let me know if you can recommend any additional areas to the above list to help to fully investigate and characterize the docking of these ligands to the protein. Also please quote me a rough estimate of your time and total price (excluding the zintro fees). Thank you!

    1. Profile Picture

      Richard |Computational Chemist

      I can do this, only I could give you Kd for each ligand. Ki is not an easy quantity to compute-you'...

      2.6 Hours Later
    2. Profile Picture

      Sonika |Assistant Professor

      Thank you for the message. I have a sound knowledge of protein structures. I also have published w...

      2.9 Hours Later
    3. Profile Picture

      Hemantkumar |Computational Chemist/ Molecular Modelle

      Hello, =Hi I have a *****ight forward project that I am hoping to get some help with. I a...

      10.1 Hours Later
    +22 Other Responses
    Area Icon

    Protein-ligand Docking

    I need your help with docking, if we could have classes, i have two protein structure to need to be docked. If you can help please contact me shortly. Thanks and regards

    1. Profile Picture

      Priya |Cofounder and Managing Director

      Hi, I am priya sankar from Xinnovem India.I can help you in docking of two protein. send me your pro...

      2.4 Hours Later
    2. Profile Picture

      Juzer |Scientist

      I am in let me know how to proceed... When to have a chat!!!!...

      4.4 Hours Later
    3. Profile Picture

      Honit |Reaserch Scientist

      Misoo, if you want to proceed, please Accept my Proposal by clicking on the Accept button....Also yo...

      3 Days Later
    +10 Other Responses
    Area Icon

    Senior Scientist Of Bioanalysis

    We are a clinical-stage biopharmaceutical company that discovers and develops novel products for the treatment of cancer. The current opening offers an opportunity to lead efforts around probody bioanalysis in a fast moving r&d environment. Responsibilities the successful candidate will: - serve as a company-wide resource in the area of large molecule bioanalysis - work closely with project teams to identify and address needs for pharmacokinetic and immunogenicity (including neutralizing antibody) analysis - select and manage vendors providing contract bioanalytical services - oversee bioanalytical method development, validation and sample analysis - innovate as necessary to meet specialized programmatic needs - troubleshoot assay performance and sample testing as needed - review bioanalytical study protocols and reports for completeness and regulatory compliance - provide guidance in development of nonclinical and clinical study protocols - train / mentor research staff and oversee wet lab activities in house requirements - phd, or pharm.D. In pharmaceutical sciences or a related field - 5-8+ years relevant industry experience supporting both preclinical activities and clinical trials - experience in quantitative bioanalysis of large molecules using ligand binding, chromatographic, mass spectrometric, or other analytical technologies - experience with immunogenicity analysis in clinical and preclinical setting - knowledge of current glp regulations, applicable guidance documents and white papers. - prior experience working in a regulated glp compliant environment - excellent communication skills and experience in working with multidisciplinary teams

      +undefined Other Responses
      Area Icon

      Drug Discovery Laboratory Automation

      We are a rd department in a pharmaceutical company. We run different assays not for screening purposes (means that the scale is relative small, maybe from 6-20 plates). Some of them are cell based assays and a sterile environment is required. At this point, we are trying to identify the areas that can be automated and looking for an outside consultant to help. Please contact me at via zintro. We are located at san francisco.Geographic focus of northern california thanks.

      1. Profile Picture

        Abdel |President

        I'd be happy to help you with that...

        1 Minute Later
      2. Profile Picture

        David |Sr. Scientist

        I have over 25 years experience in designing and building lab *****ems in a variety of env...

        1 Minute Later
      3. Profile Picture

        Srinivasan |Research Faculty

        Hello, I can help with this. I would like to know more about this opportunity. Please contact me at...

        1 Minute Later
      +27 Other Responses
      See More Inquiries

      Top Protein Ligand Experts

      See More Experts
      Share
      LinkedInTwitterFacebookGoogle+