We are looking for an analytical assay qualification expert in the development of pharmaceutical and biotechnology processes to meet we acquire, assess, or rapidly and economically develop process technology or production capabilities needed. The expert would able to guide work for analytic assay qualification used for the clinical and commercial manufacture of therapeutic proteins. This expert will plan, provide protocols and advices in support of analytical assays qualification, include development of mass spectrometric techniques, chromatographic and electrophoretic methods, in vitro potency assays to support process development, quality control and physicochemical characterization of therapeutic antibodies and antibody drug conjugates. In addition, the expert knowledge in interim reference standard, glp toxicology (in vivo portion), lot release (qa & qc) and various regulatory submissions including ind, bla, impd, etc. This expert will also be expected to direct the technical activities of junior scientists. A hands-on, laboratory-based effort will be desirable.
Areas of expertise:
seeking experts with knowledge of analytical assay qualification; analytical assay; biotechnology process; therapeutic proteins; protein synthesis; antibodies; therapeutic antibodies; antibody; biochemist; biochemistry+12 Other Responses
Good morning. My name is tony and i am a recruiter . We have a senior scientist position with a pharmaceutical company in palo alto, ca that we are looking to fill. The candidate must have a strong domain knowledge in the areas of antibody sequence analysis and antibody production/protein purification (wet-lab) and have experience with in silico tools and standards.
I was wondering if there was anything you could do to help me in my search.
Thank you for your time.....
Tony+10 Other Responses
Our company is seeking an experienced, motivated, self-sufficient scientist ii/iii for a position based in tyler, texas, usa. the ideal candidate will have significant expertise and a broad background in cellular biology, use of animal models, biochemistry and pathway analysis involving peptides and proteins in pulmonary fibrosis, in particular, and fibrotic disease, in general.
The position is funded to carry out research plans relevant to the advancement of product development. The position is physically located in wet lab space based at the biomedical research facility in tyler, texas. Candidates should be able to demonstrate a track record of independent productive research, show willingness to help guide junior lab members, have strong organizational, written, and verbal skills, and possess the ability to work both independently and as part of a laboratory team.
• develop, implement and execute both animal and cellular models to test efficacy and inform the molecular mechanisms affecting fibrosis in mammalian cells tissues, primarily of the lungs.
• rapidly onboard existing protocols and improve/augment as required
• relies on experience and judgment to plan and accomplish goals carrying out experimentation oneself
• independently design or otherwise execute studies to understand proteins and cell signaling pathways associated with tissue remodeling and fibrosis.
• evaluate and incorporate whenever possible cutting-edge technologies and models to drive creative molecular/cellular research.
• accountable for project execution, communication of results to pharmaceutical industry standards and follow-up
• collaborate broadly with members of the program teams based in austin, tx and with collaborating research groups based in tyler, tx.
• prepare and present findings at company and collaborator meetings
• ph.D. In biochemistry, cell biology, molecular biology or in vitro pharmacology, or a relevant biological field with at least 5 years of industry and/or academic experience investigating mechanism of modulation of cellular pathways preferably working with proteins and peptides
• demonstrated understanding of molecular biology, cell biology and biochemistry and hands-on experience with current techniques in protein/peptide isolation, northern/western blotting, qpcr, biochemical assays, histological sample preparation, and mammalian primary cell culture, and their use in dissecting biochemical pathways
• must have experience with in vivo animal husbandry and experimentation in rats and mice including dosing, biological sample collection, terminal procedures, multiple time point sample collections, for example for pk studies
• experience in pulmonary fibrosis specifically and familiarity with fibrotic diseases in general is necessary
• excellent interpersonal and collaborative skills, and the ability to work independently and effectively in a highly dynamic environment
• ability to multi-task to meet aggressive technology development and research goals
we can offer a varied, fast paced and interesting experience as a key contributor in growing company. We are committed to high quality, timely, well-documented science to meet our aggressive corporate development plans. in addition to competitive salaries we offer an attractive benefits package including medical, health & short-term disability insurances and a “flexible within reason” leave schedule up to 3 weeks per year.
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I am looking for an expert witness to testify regarding a variety of biochemical assays and specifically regarding the test results that these assays produce, how much effort is required to review the results of these assays, and the manner in which assay test results are reviewed and statistical analysis performed. The expert must have at least a masters or phd in biochemistry/pharmacology/cell biology or related field and expertise is drug development is preferred, as is expertise in cell-based assays to measure transcription factor inhibition. Biochemistry and pharmacology exe+16 Other Responses